This case study gives students an opportunity to draw a conclusion about an actual crime that was prosecuted in Louisiana. A physician was accused of intentionally infecting his ex-girlfriend with HIV-tainted blood drawn from a patient in his practice. The scientific investigation uses bioinformatics tools and relies on the ability to interpret phylogenetic trees. Students develop hypotheses about the crime, then use sequences and online tools to generate a phylogenetic tree to test the hypotheses and render a verdict.
To access Murder by HIV, here's the link.
NOTE: students may need to learn and practice BLAST if they haven't already acquired this skill.
Hypodermic syringe 3 by hitthatswitch under CC BY-NC-SA 2.0.